Insecticide resistance development in Aedes aegypti upon selection pressure with malathion
id: 2390
type:
Article
title: Insecticide resistance development in Aedes aegypti upon selection pressure with malathion
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creators:
name: Hidayati, H.
role: Creator
name: Nazni, W. A.
role: Creator
name: Lee, H. L.
role: Creator
name: Sofian-Azirun, M.
role: Creator
keywords:
cross-resistance
culex-quinquefasciatus
dictyoptera blattellidae
haemorrhagic fever
diptera-culicidae
house-flies
chikungunya
bioassay
aedes aegypti
resistance
mosquito control
Permethrin
lambda cyhalothrin
cyfluthrin
anopheles
mosquito
strains
language:
eng
description: Bioassay test against malathion had been carried out with larval and adult stages of Aedes aegypti. The mosquitoes were under selection pressure against malathion for forty-five consecutive generations. The rate of resistance development was measured by LC(50) and LT,, values. The larvae and adult females, after subjection to malathion selection for 45 generations, developed high resistance level to malathion, with resistance ratio of 52.7 and 3.24 folds, respectively over control mosquitoes. Cross-resistance towards the same and different groups of insecticides was determined using the F44 and F45 malathion-selected adult females. Insecticides tested were DDT (4.0%), permethrin (0.75%), propoxur (0.1%), fenitrothion (1%), gamma-cyhalothrin (0.05%) and cyfluthrin (0.15%). Results indicated that the mosquitoes were highly resistant to DDT and fenitrothion, moderately resistant to propoxur, tolerant to permethrin and lambda-cyhalothrin, and very low resistant to cyfluthrin.